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Date : 1997-03-13
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Lymphocyte signalling mechanisms subversion and ~ It begins with an overview of lymphocyte signalling and moves on to discuss the normal behavioral patterns of lymphocytes and how subversion of signalling leads to immune dysfunction
9709625 NLM Catalog Result ~ 1 Authors HarnettMargaret M RigleyKevin P Titles Lymphocyte signalling mechanisms subversion and manipulation edited by Margaret M Harnett and Kevin P
Subversion Mechanisms by Which Leishmania Parasites Can ~ This review has addressed some of the mechanisms by which Leishmania achieves this by manipulating signaling pathways of the host macrophage Such strategies to manipulate the host immune response are by no means unique to Leishmania There is increasing evidence that a great number of unicellular and pluricellular pathogens have also evolved means to inactivate or exacerbate immune cell functions contributing to their survival and the development of pathogenspecific pathologies
Subversion of B lymphocyte signaling by infectious agents ~ Finally the subversion of Blymphocyte signal transduction by infectious agents deserves consideration with respect to the critical role of signaling in autoimmunity 99 Mounting evidence
Development of T‐leukaemias in CD45 tyrosine phosphatase ~ In Harnett and Rigley eds Lymphocyte Signalling Mechanisms Subversion and Manipulation John Wiley Sons Sussex UK pp 107 – 140 Google Scholar Alexander DR 2000 The CD45 tyrosine phosphatase a positive and negative regulator of immune cell function Semin Immunol 13 in press CAS Google Scholar
Subversion of B lymphocyte tolerance by hydralazine a ~ Because the lymphocyte Erk signaling pathway is impaired in patients with active lupus 37 38 in hydralazinetreated T cells and in experimental lupus it is possible that this T cell signaling defect contributes to disease pathogenesis Our current observations suggest that the Erk signaling pathway is also impaired in B cells providing a novel potential unifying T and B cellmediated mechanism for the development of autoimmunity in both idiopathic and hydralazineinduced lupus
Signalling mechanisms underlying subversion of the immune ~ Signalling mechanisms underlying subversion of the immune response by the filarial nematode secreted product ES‐62 B1 lymphocytes B‐cell signalling The best understood mechanism of ES‐62 action is the disruption of B‐cell activation which results in the suppression of proliferation following BCR cross‐linking
Mechanisms of TLymphocyte Signaling and Activation ~ Mechanisms of TLymphocyte Signaling and Activation Takashi Saito INTRODUCTION The immune system protects us against attack by pathogens through two separate but interacting systems innate immunity and acquired or adaptive immunity
Molecular Modeling and StructureBased Design of Direct ~ Molecular Modeling and StructureBased Design of Direct Calcineurin Inhibitors Authors Authors and affiliations D J Immunophilindediated inhibition of lymphocyte Signalling in Lymphocyte Signalling Mechanisms Subversion and Manipulation ed Rigley M M H a K P John Wiley Sons Ltd 1997
Staphylococcal manipulation of host immune responses ~ A hallmark of staphylococcal infections is their frequent recurrence even when treated with antibiotics and surgical intervention which demonstrates the bacterium’s ability to manipulate innate and adaptive immune responses
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